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ORF9b plays a role in the inhibition of host innate immune response by targeting the mitochondrial-associated adapter MAVS. Mechanistically, usurps the E3 ligase ITCH to trigger the degradation of MAVS, TRAF3, and TRAF6. In addition, causes mitochondrial elongation by triggering ubiquitination and proteasomal degradation of dynamin-like protein 1/DNM1L.
COVID19 ORF9b; COVID-19 ORF9b; ORF9b; SARS-CoV-2 Open Reading Frame 9b; SARS-COV2 ORF9b
100 µL
100 µL
100 µL
100 µg
100 µL
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